Verification of the role of spiperone in the treatment of COPD through bioinformatics analysis.
Sign Up to like & getrecommendations! Published in 2021 at "International immunopharmacology"
DOI: 10.1016/j.intimp.2021.108308
Abstract: BACKGROUND Aim of this study is investigates the influence of spiperone on hydrolase activity pathway in chronic obstructive pulmonary disease (COPD). PATIENTS AND METHODS Differentially expressed genes (DEGs) were calculated by the limma package from… read more here.
Keywords: copd; regulation hydrolase; hydrolase activity; activity pathway ... See more keywords
Functional Characterization of Structural Genomics Proteins in the Crotonase Superfamily.
Sign Up to like & getrecommendations! Published in 2022 at "ACS chemical biology"
DOI: 10.1021/acschembio.1c00842
Abstract: Members of the Crotonase superfamily, a mechanistically diverse family of proteins that share a conserved quaternary structure, can often catalyze more than one reaction. However, the spectrum of activity for its members has not been… read more here.
Keywords: hydrolase activity; structural genomics; crotonase superfamily; genomics proteins ... See more keywords
Functional characterization of carboxylesterase gene mutations involved in Aphis gossypii resistance to organophosphate insecticides
Sign Up to like & getrecommendations! Published in 2017 at "Insect Molecular Biology"
DOI: 10.1111/imb.12331
Abstract: Carboxylesterases (CarEs) play an important role in detoxifying insecticides in insects. Over‐expression and structural modification of CarEs have been implicated in the development of organophosphate (OP) insecticide resistance in insects. A previous study identified four… read more here.
Keywords: hydrolase activity; resistance; carboxylesterase gene; activity ... See more keywords