Elucidating the Uncoupling of ATP Hydrolysis and Ca2+ Transport in SERCA by Sarcolipin
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DOI: 10.1016/j.bpj.2016.11.2708
Abstract: The activity of the sarco(endo)plasmic reticulum Ca2+ -ATPase (SERCA), which plays a key role in muscle contraction and relaxation, is regulated by sarcolipin (SLN), a 31-residue transmembrane peptide. Sarcolipin has been shown to uncouple ATP… read more here.
Keywords: atp hydrolysis; serca; hydrolysis ca2; ca2 transport ... See more keywords