Insights into the Allosteric Effect of SENP1 Q597A Mutation on the Hydrolytic Reaction of SUMO1 via an Integrated Computational Study
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DOI: 10.3390/molecules27134149
Abstract: Small ubiquitin-related modifier (SUMO)-specific protease 1 (SENP1) is a cysteine protease that catalyzes the cleavage of the C-terminus of SUMO1 for the processing of SUMO precursors and deSUMOylation of target proteins. SENP1 is considered to… read more here.
Keywords: hydrolytic reaction; reaction sumo1; senp1; q597a mutation ... See more keywords
Kinetic Profiling of the Hydrolytic Reaction of Benazepril: Metabolic Pathway Simulation.
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DOI: 10.5740/jaoacint.17-0121
Abstract: A simple, specific, and rapid kinetic study of benazepril (BNZ) hydrolysis was developed and validated using HPLC. BNZ was degraded using 0.1 N sodium hydroxide at room temperature to produce benazeprilat, which is an active… read more here.
Keywords: profiling; hydrolytic reaction; benazepril metabolic; profiling hydrolytic ... See more keywords