Human flavin-containing monooxygenase 1 and its long-sought hydroperoxyflavin intermediate.
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DOI: 10.1016/j.bcp.2021.114763
Abstract: Out of the five isoforms of human flavin-containing monooxygenase (hFMO), FMO1 and FMO3 are the most relevant to Phase I drug metabolism. They are involved in the oxygenation of xenobiotics including drugs and pesticides using… read more here.
Keywords: flavin containing; human flavin; containing monooxygenase; hydroperoxyflavin intermediate ... See more keywords