Encapsulating a Hydrophilic Chemotherapeutic into Rod-like Nanoparticles of a Genetically Encoded Asymmetric Triblock Polypeptide Improves its Efficacy.
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DOI: 10.1002/adfm.201605421
Abstract: Encapsulating hydrophilic chemotherapeutics into the core of polymeric nanoparticles can improve their therapeutic efficacy by increasing their plasma half-life, tumor accumulation and intracellular uptake, and by protecting them from premature degradation. To achieve these goals,… read more here.
Keywords: triblock polypeptide; hydrophilic chemotherapeutic; asymmetric triblock; polypeptide ... See more keywords