Articles with "hydrophilic interaction" as a keyword



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Comprehensive metabonomic analysis of heart tissue from isoproterenol-induced myocardial infarction rat based on reversed-phase and hydrophilic interaction chromatography coupled to mass spectrometry.

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Published in 2017 at "Journal of separation science"

DOI: 10.1002/jssc.201601013

Abstract: We aim to describe the metabonomic characteristics of myocardial infarction rats. High-performance liquid chromatography coupled with quadrupole time-of-flight mass spectrometry was utilized to develop a metabonomic method of the heart homogenates of myocardial infarction rats.… read more here.

Keywords: chromatography; reversed phase; heart; myocardial infarction ... See more keywords
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Separation of structurally related primary aliphatic amines using hydrophilic interaction chromatography with fluorescence detection after postcolumn derivatization with o-phthaldialdehyde/mercaptoethanol.

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Published in 2017 at "Journal of separation science"

DOI: 10.1002/jssc.201701005

Abstract: The retention behavior of primary aliphatic amines (homologous series of aliphatic alkyl amines and cycloalkyl amines) and positional isomers of alkylamines in the hydrophilic interaction chromatography mode was studied. The study was carried out on… read more here.

Keywords: detection; primary aliphatic; hydrophilic interaction; aliphatic amines ... See more keywords
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Influence of different hydrophilic interaction liquid chromatography stationary phases on method performance for the determination of highly polar anionic pesticides in complex feed matrices

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Published in 2021 at "Journal of Separation Science"

DOI: 10.1002/jssc.202001134

Abstract: Abstract Hydrophilic interaction liquid chromatography is an alternative liquid chromatography mode for separation of polar compounds. In the recent years, this liquid chromatography mode has been recognized as an important solution for the analysis of… read more here.

Keywords: chromatography; determination; hydrophilic interaction; performance ... See more keywords
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Comprehensive analysis of tara tannins by reversed-phase and hydrophilic interaction chromatography coupled to ion mobility and high-resolution mass spectrometry

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Published in 2019 at "Analytical and Bioanalytical Chemistry"

DOI: 10.1007/s00216-019-01931-x

Abstract: AbstractReversed-phase liquid chromatography (RP-LC) and hydrophilic interaction chromatography (HILIC) methods hyphenated to diode array detection and ion mobility (IM) high-resolution mass spectrometry (HR-MS) were used for the analysis of gallic acid derivatives and gallotannins in… read more here.

Keywords: chromatography; resolution; tara; analysis ... See more keywords
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Hydrophilic interaction liquid chromatography-mass spectrometry as a new tool for the characterization of intact semi-synthetic glycoproteins.

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Published in 2017 at "Analytica chimica acta"

DOI: 10.1016/j.aca.2017.05.020

Abstract: Improved methods for detailed characterization of complex glycoproteins are required in the growing sector of biopharmaceuticals. Hydrophilic interaction liquid chromatography (HILIC) coupled to high resolution (HR) time-of-flight mass spectrometric (TOF-MS) detection was examined for the… read more here.

Keywords: characterization intact; interaction liquid; semi synthetic; hydrophilic interaction ... See more keywords
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Hydrophilic interaction liquid chromatography of aminoglycoside antibiotics with a diol-type stationary phase.

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Published in 2018 at "Analytica chimica acta"

DOI: 10.1016/j.aca.2018.08.008

Abstract: Owing to their pronounced polarity, hydrophilic interaction liquid chromatography (HILIC) can be considered as the elective choice for the LC analysis of aminoglycoside (AG) antibiotics. In the present work, a gradient program was optimized for… read more here.

Keywords: type stationary; diol type; interaction liquid; stationary phase ... See more keywords
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Retention characteristics of some antibiotic and anti-retroviral compounds in hydrophilic interaction chromatography using isocratic elution, and gradient elution with repeatable partial equilibration.

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Published in 2019 at "Analytica chimica acta"

DOI: 10.1016/j.aca.2018.08.051

Abstract: The separation of some zwitterionic, basic and neutral antibiotic and antiretroviral compounds was studied using hydrophilic interaction chromatography (HILIC) on bare silica, bonded amide and urea superficially porous phases. The differences in the selectivity and… read more here.

Keywords: partial equilibration; equilibration; elution; hydrophilic interaction ... See more keywords
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Towards a high peak capacity of 130 using nanoflow hydrophilic interaction liquid chromatography.

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Published in 2019 at "Analytica chimica acta"

DOI: 10.1016/j.aca.2019.01.060

Abstract: Hydrophilic interaction liquid chromatography, HILIC, is a relatively new HPLC mode. Compared with other HPLC modes, HILIC is a high resolution chromatographic mode with high peak capacity for separations of complex mixtures. Although the separation… read more here.

Keywords: chromatography; high peak; interaction liquid; hydrophilic interaction ... See more keywords
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Application of hydrophilic interaction liquid chromatography for the quantification of succinylcholine in Active Pharmaceutical Ingredient and medicinal product. Identification of new impurities of succinylcholine chloride

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Published in 2018 at "Heliyon"

DOI: 10.1016/j.heliyon.2018.e01097

Abstract: A new method, using hydrophilic interaction chromatography (HILIC), for quantification of succinylcholine and impurities in Active Pharmaceutical Ingredient (API), as well as in the medicinal product, was developed. Additionally, the new impurities in API were… read more here.

Keywords: chromatography; new impurities; active pharmaceutical; hydrophilic interaction ... See more keywords
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First profiling in hydrophilic interaction liquid chromatography of intact human chorionic gonadotropin isoforms.

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Published in 2019 at "Journal of pharmaceutical and biomedical analysis"

DOI: 10.1016/j.jpba.2019.06.014

Abstract: The study of glycoproteins is a rapidly growing field, which is not surprising considering that approximately 70% of human proteins are glycosylated and that numerous biological functions are associated to the glycosylation. In this work,… read more here.

Keywords: interaction liquid; hcg; hydrophilic interaction; human chorionic ... See more keywords
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A novel hydrophilic interaction liquid chromatography method for the analysis of arterolane; Isolation and structural elucidation of its major degradation product by LC-HRMS and NMR.

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Published in 2020 at "Journal of pharmaceutical and biomedical analysis"

DOI: 10.1016/j.jpba.2020.113279

Abstract: Adequate retention of arterolane (ART) has not been published in the literature till date; the hydrophilic interaction liquid chromatographic (HILIC) method with improved retention and separation of arterolane from its degradation products are reporting here… read more here.

Keywords: degradation; interaction liquid; method; hydrophilic interaction ... See more keywords