One-step preparation of cyclen-containing hydrophilic polymeric monolithic materials via epoxy-amine ring-opening reaction and their application in enrichment of N-glycopeptides.
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DOI: 10.1016/j.talanta.2020.122049
Abstract: Considering the special structure of 1,4,7,10-tetraazacyclododecane (cyclen) which is easy to form complexes with ions, it is beneficial to achieve particular selectivity. Cyclen was selected as a precursor to react with triglycidyl isocyanurate (TGIC), and… read more here.
Keywords: epoxy amine; cyclen; hydrophilic polymeric; via epoxy ... See more keywords
Sustained Release of Poorly Water-Soluble Drug from Hydrophilic Polymeric Film Sandwiched Between Hydrophobic Layers
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DOI: 10.1208/s12249-018-1089-x
Abstract: This proof-of-concept study explores the feasibility of using a drug-loaded hydrophilic polymeric layer sandwiched between two hydrophobic layers for improving film drug load while achieving sustained release of poorly water-soluble drug. Such films having total… read more here.
Keywords: water; hydrophilic polymeric; drug; sustained release ... See more keywords