Articles with "hydrophobic bridge" as a keyword



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Role of the Hydrophobic Bridge in the Carbapenemase Activity of Class D β-Lactamases

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Published in 2018 at "Antimicrobial Agents and Chemotherapy"

DOI: 10.1128/aac.02191-18

Abstract: Class D carbapenemases are enzymes of the utmost clinical importance due to their ability to confer resistance to the last-resort carbapenem antibiotics. We investigated the role of the conserved hydrophobic bridge in the carbapenemase activity… read more here.

Keywords: carbapenemase activity; class; carbapenemase; bridge ... See more keywords