Protein–Ligand interactions for hydrophobic charge-induction chromatography: A QCM-D study
Sign Up to like & getrecommendations! Published in 2022 at "Applied Surface Science"
DOI: 10.1016/j.apsusc.2021.151420
Abstract: Abstract Hydrophobic charge-induction chromatography (HCIC) is a novel technology for antibody purification. The interaction between immunoglobulin G (IgG) and HCIC ligands was investigated by dissipative quartz crystal microbalance (QCM-D). HCIC ligands 2-mercapto-1-methylimidazole (MMI), 2-mercaptobenzimidazole (MBI)… read more here.
Keywords: protein; induction chromatography; hydrophobic charge; charge induction ... See more keywords
Evaluation on adsorption selectivity of immunoglobulin G with 2-mercapto-1-methyl-imidazole-based hydrophobic charge-induction resins
Sign Up to like & getrecommendations! Published in 2017 at "Biochemical Engineering Journal"
DOI: 10.1016/j.bej.2016.12.005
Abstract: Abstract Hydrophobic charge-induction chromatography (HCIC) with 2-mercapto-1-methyl-imidazole (MMI) ligands shows promising results in antibody purification. In this study, competitive adsorption processes between bovine immunoglobulin G (IgG) and bovine serum albumin (BSA) were investigated with MMI… read more here.
Keywords: adsorption; hydrophobic charge; charge induction; mercapto methyl ... See more keywords