A hydrophobic gate in the inner pore helix is the major determinant of inactivation in mechanosensitive Piezo channels
Sign Up to like & getrecommendations! Published in 2019 at "eLife"
DOI: 10.7554/elife.44003
Abstract: Piezo1 and Piezo2 belong to a family of mechanically-activated ion channels implicated in a wide range of physiological processes. Mechanical stimulation triggers Piezo channels to open, but their characteristic fast inactivation process results in rapid… read more here.
Keywords: helix; channels hydrophobic; inactivation; piezo channels ... See more keywords