OleD Loki as a Catalyst for Hydroxamate Glycosylation
Sign Up to like & getrecommendations! Published in 2019 at "ChemBioChem"
DOI: 10.1002/cbic.201900601
Abstract: Herein we describe the ability of the permissive glycosyltransferase (GT) OleD Loki to convert a diverse set of >15 histone deacetylase (HDAC) inhibitors (HDACis) into their corresponding hydroxamate glycosyl esters. Representative glycosyl esters were subsequently… read more here.
Keywords: hydroxamate glycosylation; catalyst hydroxamate; oled loki; loki catalyst ... See more keywords
Probing the interactions of hydroxamic acid and mineral surfaces: Molecular mechanism underlying the selective separation
Sign Up to like & getrecommendations! Published in 2019 at "Chemical Engineering Journal"
DOI: 10.1016/j.cej.2019.05.152
Abstract: Abstract Separation process facilitated by selective adsorption of chemical reagents can be modulated through an in-depth understanding of reagent-surface interaction, which is of both fundamental and practical importance in a wide range of industrial applications.… read more here.
Keywords: interactions hydroxamic; hydroxamate; probing interactions; separation ... See more keywords
Targeted Polypharmacology: Discovery of a Highly Potent Non-Hydroxamate Dual Matrix Metalloproteinase (MMP)-10/-13 Inhibitor.
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DOI: 10.1021/acs.jmedchem.7b01001
Abstract: Matrix metalloproteinases (MMPs) play a key role in many diseases like cancer, atherosclerosis or arthritis. Interest in MMP inhibition has been revitalized very recently as the knowledge on the underlying network of biological pathways is… read more here.
Keywords: non hydroxamate; targeted polypharmacology; matrix; mmp ... See more keywords
A stable lanthanum hydroxamate metal-organic framework with radical character and electrical conductivity.
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DOI: 10.1039/d2dt02340g
Abstract: Metal-organic frameworks with hydroxamate linkers are an emerging new class of stable porous crystalline materials. Due to the difficulty in controlling reversible formation of strong metal-hydroxamate bonds and the limitation of available hydroxamate ligands, hydroxamate… read more here.
Keywords: framework; metal organic; conductivity; lanthanum ... See more keywords