Cell-free biosynthesis of ω-hydroxy acids boosted by a synergistic combination of alcohol dehydrogenases.
Sign Up to like & getrecommendations! Published in 2022 at "ChemSusChem"
DOI: 10.1002/cssc.202200397
Abstract: The activity orchestration of an unprecedented cell-free enzyme system with self-sufficient cofactor recycling enables the step-wise transformation of aliphatic diols into ω-hydroxy acids at the expense of molecular oxygen as electron acceptor. The efficiency of… read more here.
Keywords: alcohol dehydrogenases; system; cell free; hydroxy acids ... See more keywords
Highly Efficient Deracemization of Racemic 2-Hydroxy Acids in a Three-Enzyme Co-Expression System Using a Novel Ketoacid Reductase
Sign Up to like & getrecommendations! Published in 2018 at "Applied Biochemistry and Biotechnology"
DOI: 10.1007/s12010-018-2760-0
Abstract: Enantiopure 2-hydroxy acids (2-HAs) are important intermediates for the synthesis of pharmaceuticals and fine chemicals. Deracemization of racemic 2-HAs into the corresponding single enantiomers represents an economical and highly efficient approach for synthesizing chiral 2-HAs… read more here.
Keywords: deracemization; hydroxy acids; ketoacid reductase; deracemization racemic ... See more keywords
Resolving Enantiomers of 2-Hydroxy Acids by Nuclear Magnetic Resonance.
Sign Up to like & getrecommendations! Published in 2022 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.2c00490
Abstract: Biologically important 2-hydroxy carboxylates such as lactate, malate, and 2-hydroxyglutarate exist in two enantiomeric forms that cannot be distinguished under achiral conditions. The D and L (or R, S) enantiomers have different biological origins and… read more here.
Keywords: magnetic resonance; nuclear magnetic; enantiomers hydroxy; hydroxy acids ... See more keywords
Efficient Access to Sequence-Controlled Poly(α-hydroxy acids) with Ax(BC)yDz-Type and Ax(BC)yAz-Type Triblock Structures via Self-Switchable Ring-Opening Polymerization of Monomer Mixtures.
Sign Up to like & getrecommendations! Published in 2023 at "ACS macro letters"
DOI: 10.1021/acsmacrolett.3c00211
Abstract: Synthesizing block-sequence-controlled poly(α-hydroxy acids) of three or four α-hydroxy acids remains challenging in one step. In this study, a strategy was employed using three monomers of O-carboxyanhydrides (OCAs) consisting of one α-hydroxy acid (A), asymmetric… read more here.
Keywords: sequence controlled; via self; sequence; hydroxy acids ... See more keywords
Are cosmetics based on alpha hydroxy acids safe to use when purchased over the internet?
Sign Up to like & getrecommendations! Published in 2022 at "Toxicology and Industrial Health"
DOI: 10.1177/07482337221126771
Abstract: Alpha hydroxy acids (AHAs) are used in dermatology for topical treatment of skin disorders. Some regulatory bodies, including Food and Drug Administration (FDA), recommended labeling cosmetic products with sunburn alerts and proposed limitations regarding concentrations… read more here.
Keywords: alpha hydroxy; acids safe; cosmetics based; cosmetic products ... See more keywords
Alpha Hydroxy Acids
Sign Up to like & getrecommendations! Published in 2017 at "International Journal of Toxicology"
DOI: 10.1177/1091581817716656
Abstract: While Glycolic and Lactic acid peeling agents have equivalent results, the following shows that lactic acid peels have many benefits over glycolic acid peels. Glycolic Acid is the most commonly used AHA. Because of its… read more here.
Keywords: alpha hydroxy; hydroxy acids; acid; glycolic acid ... See more keywords
Differential Oligomerization of Alpha versus Beta Amino Acids and Hydroxy Acids in Abiotic Proto-Peptide Synthesis Reactions
Sign Up to like & getrecommendations! Published in 2022 at "Life"
DOI: 10.3390/life12020265
Abstract: The origin of biopolymers is a central question in origins of life research. In extant life, proteins are coded linear polymers made of a fixed set of twenty alpha-L-amino acids. It is likely that the… read more here.
Keywords: amino acids; beta amino; hydroxy acids; alpha versus ... See more keywords
Synthesis of Terpineol from Alpha-Pinene Catalyzed by α-Hydroxy Acids
Sign Up to like & getrecommendations! Published in 2022 at "Molecules"
DOI: 10.3390/molecules27031126
Abstract: We report the use of five alpha-hydroxy acids (citric, tartaric, mandelic, lactic and glycolic acids) as catalysts in the synthesis of terpineol from alpha-pinene. The study found that the hydration rate of pinene was slow… read more here.
Keywords: pinene; synthesis terpineol; hydroxy acids; alpha pinene ... See more keywords
Extraction of Isoflavones, Alpha-Hydroxy Acids, and Allantoin from Soybean Leaves—Optimization by a Mixture Design of the Experimental Method
Sign Up to like & getrecommendations! Published in 2023 at "Molecules"
DOI: 10.3390/molecules28093963
Abstract: Soybeans are commonly known as a valuable source of biologically active compounds including isoflavones as well as allantoin and alpha-hydroxy acids. Since these compounds exhibit skin therapeutic effects, they are widely used in the cosmetic… read more here.
Keywords: alpha hydroxy; mixture; extraction; hydroxy acids ... See more keywords