An efficient and rapid synthesis of 3-hydroxy-3-alkyl-2-oxindoles via Zn-mediated barbier-type reaction under aqueous conditions
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DOI: 10.1007/s12039-017-1329-8
Abstract: Abstract A robust and rapid synthesis of 3-hydroxy-3-alkyl-2-oxindoles from isatins is described. This method introduces an ecofriendly, un-activated Zn dust, solid $$\hbox {NH}_{4}\hbox {Cl}$$NH4Cl and substrates under aqueous conditions, which has produced the product in moderate… read more here.
Keywords: alkyl oxindoles; rapid synthesis; aqueous conditions; synthesis hydroxy ... See more keywords