A novel aptamer-based online magnetic solid phase extraction method for the selective determination of 8-hydroxy-2'-deoxyguanosine in human urine.
Sign Up to like & getrecommendations! Published in 2018 at "Analytica chimica acta"
DOI: 10.1016/j.aca.2017.12.032
Abstract: In this work, an innovative magnetic aptamer adsorbent (Fe3O4-aptamer MNPs) was synthesized for the selective extraction of 8-hydroxy-2'-deoxyguanosine (8-OHdG). Amino-functionalized-Fe3O4 was crosslinked with 8-OHdG aptamer by glutaraldehyde and fixed into a steel stainless tube as… read more here.
Keywords: hydroxy deoxyguanosine; extraction; phase extraction; magnetic solid ... See more keywords
Blood-based 8-hydroxy-2'-deoxyguanosine level: a potential diagnostic biomarker for Atrial Fibrillation.
Sign Up to like & getrecommendations! Published in 2020 at "Heart rhythm"
DOI: 10.1016/j.hrthm.2020.09.017
Abstract: BACKGROUND Recent research findings revealed key role for oxidative DNA damage in the pathogenesis of atrial fibrillation (AF). Therefore, a circulating oxidative DNA damage marker 8-hydroxy-2'-deoxyguanosine (8-OHdG) may represent a biomarker to stage AF and… read more here.
Keywords: atrial fibrillation; hydroxy deoxyguanosine; recurrence; biomarker ... See more keywords
An electrochemical aptasensor for the highly sensitive detection of 8-hydroxy-2'-deoxyguanosine based on the hybridization chain reaction.
Sign Up to like & getrecommendations! Published in 2018 at "Talanta"
DOI: 10.1016/j.talanta.2017.11.036
Abstract: In the present work a highly sensitive and selective aptasensor was developed for the determination of 8-hydroxy-2'-deoxyguanosine (8-OH-dG) based on the hybridization chain reaction (HCR) signal amplification. It was observed that the aptamer of 8-OH-dG… read more here.
Keywords: based hybridization; hydroxy deoxyguanosine; detection; deoxyguanosine based ... See more keywords
Reduced graphene oxide-ZnO nanocomposite based electrochemical sensor for sensitive and selective monitoring of 8-hydroxy-2'-deoxyguanosine.
Sign Up to like & getrecommendations! Published in 2018 at "Talanta"
DOI: 10.1016/j.talanta.2018.04.028
Abstract: Developing reliable and feasible electrochemical sensors for the detection of 8-hydroxy-2'-deoxyguanosine (8-OHdG) is important because the urinary level of 8-OHdG is related to cancer disease. Moreover, the co-existed uric acid (UA) as an interference severe… read more here.
Keywords: graphene oxide; hydroxy deoxyguanosine; rgo; zno rgo ... See more keywords
ALTERED BLOOD AND AQUEOUS HUMOR LEVELS OF ASPROSIN, 4-HYDROXYNONENAL, AND 8-HYDROXY-DEOXYGUANOSINE IN PATIENTS WITH DIABETES MELLITUS AND CATARACT WITH AND WITHOUT DIABETIC RETINOPATHY.
Sign Up to like & getrecommendations! Published in 2020 at "Retina"
DOI: 10.1097/iae.0000000000002776
Abstract: PURPOSE Diabetic retinopathy (DRP) is the formation of edema and small vessels in the retina due to high blood glucose levels. Asprosin is a hormone that stimulates the release of glucose from the liver into… read more here.
Keywords: blood; levels asprosin; hydroxy deoxyguanosine; blood aqueous ... See more keywords
Elevated Plasma Level of 8-Hydroxy-2′-deoxyguanosine Is Associated with Primary Open-Angle Glaucoma
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Ophthalmology"
DOI: 10.1155/2020/6571413
Abstract: Purpose To determine the association between plasma 8-hydroxy-2′-deoxyguanosine (8-OHdG) levels, a marker for oxidative DNA damage, and patients with primary open-angle glaucoma (POAG) or its clinical phenotypes. Furthermore, we also examined the utility of plasma… read more here.
Keywords: poag; hydroxy deoxyguanosine; elevated plasma; plasma ... See more keywords
Antioxidant defense system versus 8-hydroxy-2’-deoxyguanosine; a short look to recent findings
Sign Up to like & getrecommendations! Published in 2018 at "Journal of renal injury prevention"
DOI: 10.15171/jrip.2018.29
Abstract: Implication for health policy/practice/research/medical education: The impact of 8-hydroxy-2’ -deoxyguanosine as an oxidative stress biomarker has been detected in many diseases, including bladder and prostate cancer, rheumatoid arthritis and renal disease. Please cite this paper… read more here.
Keywords: system versus; hydroxy deoxyguanosine; deoxyguanosine; antioxidant defense ... See more keywords
Pre-Treatment Physical Activity Could Positively Influence Pregnancy Rates in IVF despite the Induced Oxidative Stress: A Cohort Study on Salivary 8-Hydroxy-2′-deoxyguanosine
Sign Up to like & getrecommendations! Published in 2022 at "Antioxidants"
DOI: 10.3390/antiox11081586
Abstract: (1) Background: This study was designed to define whether pretreatment habitual physical activity (PA)-induced oxidative stress (OS) influences outcome measures by using 8-hydroxy-2′-deoxyguanosine (8-OHdG) in saliva samples of patients undergoing in vitro fertilization (IVF). (2)… read more here.
Keywords: hydroxy deoxyguanosine; oxidative stress; physical activity; induced oxidative ... See more keywords
Changes in Urinary Hydrogen Peroxide and 8-Hydroxy-2′-Deoxyguanosine Levels after a Forest Walk: A Pilot Study
Sign Up to like & getrecommendations! Published in 2018 at "International Journal of Environmental Research and Public Health"
DOI: 10.3390/ijerph15091871
Abstract: Some studies have shown that exposure to forests has positive effects on human health, although the mechanisms underlying the health benefits of a forest environment have not been elucidated yet. The current study was aimed… read more here.
Keywords: hydroxy deoxyguanosine; hydrogen peroxide; walk; urinary hydrogen ... See more keywords
A Sensitive FRET Biosensor Based on Carbon Dots-Modified Nanoporous Membrane for 8-hydroxy-2′-Deoxyguanosine (8-OHdG) Detection with Au@ZIF-8 Nanoparticles as Signal Quenchers
Sign Up to like & getrecommendations! Published in 2020 at "Nanomaterials"
DOI: 10.3390/nano10102044
Abstract: A sensitive fluorescence resonance energy transfer (FRET) biosensor is proposed to detect 8-hydroxy-2′-deoxyguanosine (8-OHdG), which is a typical DNA oxidation damage product excreted in human urine. The FRET biosensor was based on carbon dots (CDs)-modified… read more here.
Keywords: hydroxy deoxyguanosine; detection; biosensor; zif nanoparticles ... See more keywords