NUCLEOPHILIC SUBSTITUTION OF A 4-DIMETHYLAMINO GROUP IN QUINOLINE PROTON SPONGES. STABILIZATION OF 4-QUINOLONES IN HYDROXY FORM. SYNTHESIS OF A PROTON SPONGE BASED ON 8-HYDROXYQUINOLINE
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DOI: 10.1007/5301
Abstract: Demethylation of methoxy groups in 6(8)-methoxy-2,4,5-tris(dimethylamino)quinolines with 48% HBr leads to nucleophilic substitution of the 4-NMe2 group with the formation of quinolones existing in solution and the solid state in the hydroxy form stabilized by… read more here.
Keywords: nucleophilic substitution; dimethylamino; hydroxy form; group ... See more keywords
Nucleophilic substitution of a 4-dimethylamino group in quinoline proton sponges. Stabilization of 4-quinolones in hydroxy form. Synthesis of a proton sponge based on 8-hydroxyquinoline
Sign Up to like & getrecommendations! Published in 2019 at "Chemistry of Heterocyclic Compounds"
DOI: 10.1007/s10593-019-02587-2
Abstract: Demethylation of methoxy groups in 6(8)-methoxy-2,4,5-tris(dimethylamino)quinolines with 48% HBr leads to nucleophilic substitution of the 4-NMe2 group with the formation of quinolones existing in solution and the solid state in the hydroxy form stabilized by… read more here.
Keywords: nucleophilic substitution; dimethylamino; hydroxy form; group ... See more keywords