Synthesis and antiviral activity of 1-hydroxy-2-(2-hydroxyphenyl)imidazoles against vaccinia virus
Sign Up to like & getrecommendations! Published in 2019 at "Russian Chemical Bulletin"
DOI: 10.1007/s11172-019-2467-6
Abstract: Abstract2-(2-Hydroxyplienyl)imidazole derivatives were synthesized and tested for antiviral activity against vaccinia virus in Vero cell culture. 1-Methylimidazole 3-oxides, 1-methoxyimidazoles, and 1H-imidazoles showed no activity, whereas some 1-hydroxyimidazole derivatives hold promise, exhibiting antiviral activity and weak… read more here.
Keywords: activity hydroxy; antiviral activity; vaccinia virus; hydroxy hydroxyphenyl ... See more keywords
Isolation and characterization of 2-hydroxy-3-[4-hydroxyphenyl]-2-propenoic acid and 4-bromophenol from anti-diabetic extract of the root bark of Uvaria afzelii
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DOI: 10.1016/j.sajb.2017.05.006
Abstract: Abstract The anti-diabetic activity of the methanolic extract of Uvaria afzelii (Annonaceae) root bark was investigated in normoglycaemic, glucose and alloxan-induced diabetic rats using glibenclamide (5 mg/kg) and normal saline as positive and negative controls respectively.… read more here.
Keywords: hydroxy hydroxyphenyl; acid bromophenol; anti diabetic; spectroscopy ... See more keywords
Exploring binding stability of hydroxy-3-(4-hydroxyphenyl)-5-(4-nitrophenyl)-5,5a,7,8,9,9a-hexahydrothiazolo[2,3-b] quinazolin-6-one with T790M/L858R EGFR-TKD
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Biomolecular Structure and Dynamics"
DOI: 10.1080/07391102.2022.2053748
Abstract: Abstract Cancer causes innumerable deaths every year globally. Breast cancer and non-small cell lung carcinoma are the most prevalent worldwide. EGFR-TKD is a neoplastic survival therapeutic target in a wide array of carcinoma cells. Various… read more here.
Keywords: tkd; hydroxyphenyl nitrophenyl; egfr tkd; hydroxy hydroxyphenyl ... See more keywords