Biological Screening and Crystallographic Studies of Hydroxy γ-Lactone Derivatives to Investigate PPARγ Phosphorylation Inhibition
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DOI: 10.3390/biom13040694
Abstract: PPARγ represents a key target for the treatment of type 2 diabetes and metabolic syndrome. To avoid serious adverse effects related to the PPARγ agonism profile of traditional antidiabetic drugs, a new opportunity is represented… read more here.
Keywords: biological screening; phosphorylation; ppar phosphorylation; hydroxy lactone ... See more keywords