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Published in 2018 at "Chemistry of Heterocyclic Compounds"
DOI: 10.1007/s10593-018-2360-5
Abstract: The regioisomeric 6-hydroxy-4-methyl- and 4-hydroxy-6-methylaurones were synthesized. Aminomethylation by the action of aminals of secondary amines was investigated. It was shown that the reaction proceeds selectively with the formation of 7-aminomethyl-6-hydroxy-4-methyl- and 5-aminomethyl-4-hydroxy-6-methylaurones, respectively. The…
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Keywords:
hydroxy methylaurones;
methyl hydroxy;
regioisomeric hydroxy;
hydroxy methyl ... See more keywords
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Published in 2019 at "Chemistry of Heterocyclic Compounds"
DOI: 10.1007/s10593-019-02542-1
Abstract: Herein, we report the studies of the multicomponent reaction of 5-hydroxy-2-methyl-4H-pyran-4-one with carbonyl compounds and Meldrum's acid. General methods for the synthesis of 6-methyl-3,4-dihydropyrano[3,2-b]pyran-2,8-diones, 3-(3-hydroxy-6-methyl-4-oxo-4H-pyran-2-yl)propanoic acid amides and esters, as well as 7-oxo-7H-furo[3,2-b]pyran-3-ylacetic acids were…
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Keywords:
methyl;
multicomponent reaction;
hydroxy methyl;
reaction hydroxy ... See more keywords
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Published in 2017 at "Journal of Porous Materials"
DOI: 10.1007/s10934-017-0414-1
Abstract: Highly ordered mesoporous MCM-41 and SBA-15 have been synthesized and functionalized with different amounts of propyl sulfonic acid groups using 3-mercaptopropyltrimethoxysilane as sulfur source. The synthesized catalysts have been well-characterized by different techniques such as…
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Keywords:
acid;
methyl coumarin;
yield hydroxy;
hydroxy methyl ... See more keywords
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Published in 2018 at "Russian Chemical Bulletin"
DOI: 10.1007/s11172-018-2301-6
Abstract: A convenient method was developed for the synthesis of previously unknown 1,2-diketones, based on the condensation of 5-hydroxy-2-methyl-4H-pyran-4-one with arylglyoxals. The study demonstrated the possibility of using these compounds to synthesize nitrogen-containing hetero cyclic systems…
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Keywords:
methyl;
hydroxy methyl;
condensation hydroxy;
methyl pyran ... See more keywords
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Published in 2021 at "Animal Feed Science and Technology"
DOI: 10.1016/j.anifeedsci.2021.114889
Abstract: Abstract Positive effects of β-hydroxy β-methyl butyrate (HMB) on reproductive performance, growth rate and health have been reported in both human and animal studies. However, research into its effect on sow and litter performance is…
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Keywords:
piglet;
performance;
hmb;
hydroxy methyl ... See more keywords
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Published in 2017 at "Atmospheric Environment"
DOI: 10.1016/j.atmosenv.2017.07.038
Abstract: Abstract The reaction of 4-hydroxy-4-methyl-2-pentanone (4H4M2P) with Cl atoms was studied for the first time experimentally and theoretically. Relative kinetic measurements were carried out at room temperature and 1 bar of synthetic air/N 2 in two…
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Keywords:
methyl pentanone;
rate;
reaction;
hydroxy methyl ... See more keywords
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Published in 2018 at "Journal of Molecular Structure"
DOI: 10.1016/j.molstruc.2018.05.075
Abstract: Abstract Two binuclear Pd (II) and Ir(IV) complexes with new bis [4-hydroxy-6-methyl-3-{(1E)-N-[2-(ethylamino) ethyl] ethanimidoyl}-2H-pyran-2-one] ligand (Schiff base: L) have been prepared and characterized by elemental analysis, ESI-MS, conductivity, NMR (1H NMR, 13C NMR, COSY-NMR, HMBC-NMR…
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Keywords:
ethylamino ethyl;
hydroxy methyl;
geometry;
methyl ethylamino ... See more keywords
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Published in 2017 at "Journal of medicinal chemistry"
DOI: 10.1021/acs.jmedchem.7b00846
Abstract: Certain classes of neuroactive steroids (NASs) are positive allosteric modulators (PAM) of synaptic and extrasynaptic GABAA receptors. Herein, we report new SAR insights in a series of 5β-nor-19-pregnan-20-one analogues bearing substituted pyrazoles and triazoles at…
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Keywords:
neuroactive steroids;
pregnan one;
hydroxy methyl;
methyl cyano ... See more keywords
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Published in 2021 at "ACS Omega"
DOI: 10.1021/acsomega.1c00447
Abstract: The re-emergence of Chikungunya virus (CHIKV) infection in humans with no approved antiviral therapies or vaccines is one of the major problems with global significance. In the present investigation, we screened 80 in-house quinoline derivatives…
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Keywords:
hydroxy methyl;
chikv;
inhibition;
infection ... See more keywords
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Published in 2018 at "Synthetic Communications"
DOI: 10.1080/00397911.2018.1500426
Abstract: Abstract 2-(3-Cyano-5-hydroxy-4,5-dimethyl-1H-pyrrol-2(5H)-ylidene)malononitrile was synthesized by the interaction between malononitrile dimer and diacetyl. It reacts with aldehydes in ethanol in the presence of ammonium acetate at room temperature and results 2-(3-cyano-5-hydroxy-5-methyl-4-vinylene-1H-pyrrol-2(5H)-ylidene)malononitriles in 66–86% yield. The developed…
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Keywords:
methyl vinylene;
hydroxy methyl;
cyano hydroxy;
pyrrol ylidene ... See more keywords
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Published in 2022 at "NeuroReport"
DOI: 10.1097/wnr.0000000000001769
Abstract: Objective Numerous studies suggest that the a-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid-type (AMPA) receptor appears to play a central role in mediating brain functions, such as learning and memory. Trafficking of this receptor is related to different long-term memory…
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Keywords:
role;
amino hydroxy;
memory;
receptor ... See more keywords