Articles with "hydroxy quinolone" as a keyword



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Chemistry of 4-Hydroxy-2(1H)-quinolone. Part 1: Synthesis and reactions

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Published in 2017 at "Arabian Journal of Chemistry"

DOI: 10.1016/j.arabjc.2014.01.012

Abstract: Abstract This review summarizes results from the literature concerning the synthesis and chemical reactivity of 4-hydroxy-2(1 H )-quinolone as well as its reactions that are reported. Most imaginable reaction types have been successfully applied and… read more here.

Keywords: chemistry hydroxy; chemistry; hydroxy quinolone; quinolone part ... See more keywords
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Composition, stability and fluorescence properties of metal complexes of an aza-flavonol analog 1-methyl-2-phenyl-3-hydroxy-4(1H)-quinolone in aqueous solution

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Published in 2020 at "Inorganica Chimica Acta"

DOI: 10.1016/j.ica.2020.119471

Abstract: Abstract Aza-flavonols are compounds containing the 3-hydroxy-4(1H)-quinolone moiety, a unique scaffold with applications expanding from fluorescent probes and bioimaging to potential metal-related pharmaceutical drugs. Compositions and stability constants of metal complexes of an aza-flavonol 1-methyl-2-phenyl-3-hydroxy-4(1H)-quinolone… read more here.

Keywords: fluorescence; aza flavonol; metal complexes; hydroxy quinolone ... See more keywords

Discovery of N-quinazolinone-4-hydroxy-2-quinolone-3-carboxamides as DNA gyrase B-targeted antibacterial agents

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Published in 2022 at "Journal of Enzyme Inhibition and Medicinal Chemistry"

DOI: 10.1080/14756366.2022.2084088

Abstract: Abstract Emerging drug resistance is generating an urgent need for novel and effective antibiotics. A promising target that has not yet been addressed by approved antibiotics is the bacterial DNA gyrase subunit B (GyrB), and… read more here.

Keywords: hydroxy quinolone; targeted antibacterial; dna gyrase; quinolone carboxamides ... See more keywords