Chemoenzymatic Oxosulfonylation-Bioreduction Sequence for the Stereoselective Synthesis of β-Hydroxy Sulfones.
Sign Up to like & getrecommendations! Published in 2021 at "ChemSusChem"
DOI: 10.1002/cssc.202101313
Abstract: A series of optically active β-hydroxy sulfones has been obtained through an oxosulfonylation-stereoselective reduction sequence in aqueous medium. Firstly, β-keto sulfones were synthesized from arylacetylenes and sodium sulfinates to subsequently develop the carbonyl reduction in… read more here.
Keywords: hydroxy; hydroxy sulfones; sequence; synthesis ... See more keywords
A substitution/dynamic kinetic resolution – Asymmetric transfer hydrogenation tandem process for preparation of stereocenters β-hydroxy sulfones
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DOI: 10.1016/j.mcat.2018.04.019
Abstract: Abstract A noval method for the synthesis of optically active β-hydroxy sulfones was developed. Through a substitution/dynamic kinetic resolution–asymmetric transfer hydrogenation, the presented method was based on one-pot enantioselective organic transformations of α–bromoindenones and sodium… read more here.
Keywords: resolution asymmetric; hydroxy sulfones; kinetic resolution; dynamic kinetic ... See more keywords
Hydrogenation of β-Keto Sulfones to β-Hydroxy Sulfones with Alkyl Aluminum Compounds: Structure of Intermediate Hydroalumination Products
Sign Up to like & getrecommendations! Published in 2022 at "Molecules"
DOI: 10.3390/molecules27072357
Abstract: β-Hydroxy sulfones are important in organic synthesis. The simplest method of β-hydroxy sulfones synthesis is the hydrogenation of β-keto sulfones. Herein, we report the reducing properties of alkyl aluminum compounds R3Al (R = Et, i-Bu,… read more here.
Keywords: alkyl aluminum; hydrogenation keto; aluminum compounds; hydroxy sulfones ... See more keywords