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Published in 2019 at "Oxidative Medicine and Cellular Longevity"
DOI: 10.1155/2019/5937326
Abstract: Recent studies indicate that 4-hydroxy-trans-2-nonenal (HNE), a major oxidative stress triggered lipid peroxidation-derived aldehyde, plays a critical role in the pathophysiology of various human pathologies including metabolic syndrome, diabetes, cardiovascular, neurological, immunological, and age-related diseases…
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Keywords:
signaling pathways;
oxidative pro;
trans nonenal;
hydroxy trans ... See more keywords
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Published in 2022 at "Biomolecules"
DOI: 10.3390/biom12010145
Abstract: 4-hydroxy-2,3-trans-nonenal (C9H16O2), also known as 4-hydroxy-2E-nonenal (C9H16O2; HNE) is an α,β-unsaturated hydroxyalkenal. HNE is a major aldehyde, formed in the peroxidation process of ω-6 polyunsaturated fatty acids (ω-6 PUFAs), such as linoleic and arachidonic acid.…
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Keywords:
chemistry;
trans nonenal;
hydroxy trans;
chemistry biochemistry ... See more keywords