Regioselective Synthesis of 2-Aryl-5-cyano-1-(2-hydroxyaryl)-1H-imidazole-4-carboxamides Self-Assisted by a 2-Hydroxyaryl Group
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DOI: 10.1021/acsomega.2c01399
Abstract: The reactivity of the diaminomaleonitrile-based imines containing hydroxyphenyl substituents with diverse aromatic aldehydes has been explored for the synthesis of novel highly substituted nitrogen heterocycles, which are considered privileged scaffolds in drug discovery. We report… read more here.
Keywords: cyano hydroxyaryl; hydroxyaryl imidazole; synthesis; group ... See more keywords
DABCO- and DBU-promoted one-pot reaction of N-sulfonyl ketimines with Morita–Baylis–Hillman carbonates: a sequential approach to (2-hydroxyaryl)nicotinate derivatives
Sign Up to like & getrecommendations! Published in 2018 at "Beilstein Journal of Organic Chemistry"
DOI: 10.3762/bjoc.14.254
Abstract: An intriguing DABCO-catalyzed and DBU-promoted one-pot synthesis of an important class of (2-hydroxyaryl)pyridine derivatives bearing a carboxylate or a nitrile group suitably placed at C3 position of the aza-ring has been achieved in acceptable chemical… read more here.
Keywords: hydroxyaryl; one pot; promoted one; dbu promoted ... See more keywords