p-Hydroxybenzyl Alcohol Antagonized the ROS-Dependent JNK/Jun/Caspase-3 Pathway to Produce Neuroprotection in a Cellular Model of Parkinson’s Disease
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DOI: 10.3390/nu14235002
Abstract: Parkinson’s disease (PD) is a progressive disorder that affects brain nerve cells responsible for body motion and remains incurable. p-Hydroxybenzyl alcohol (HBA) is the primary phenolic compound in Gastrodiae Rhizoma, known for its therapeutic benefits… read more here.
Keywords: parkinson disease; caspase; hba; parkinson ... See more keywords
P‑hydroxybenzyl alcohol ameliorates neuronal cerebral ischemia‑reperfusion injury by activating mitochondrial autophagy through SIRT1
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DOI: 10.3892/mmr.2023.12955
Abstract: Mitochondrial autophagy serves a key role in clearing damaged mitochondria. P-hydroxybenzyl alcohol (pHBA) can improve neuronal injury induced by cerebral ischemia-reperfusion (I/R). However, the mechanism of pHBA improving I/R damage through the mitochondrial pathway remains… read more here.
Keywords: hydroxybenzyl alcohol; reperfusion; injury; mitochondrial autophagy ... See more keywords