Improved 11α-hydroxycanrenone production by modification of cytochrome P450 monooxygenase gene in Aspergillus ochraceus
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DOI: 10.2478/acph-2021-0004
Abstract: Abstract Eplerenone is a drug that protects the cardiovascular system. 11α-Hydroxycanrenone is a key intermediate in eplerenone synthesis. We found that although the cytochrome P450 (CYP) enzyme system in Aspergillus ochraceus strain MF018 could catalyse… read more here.
Keywords: monooxygenase; production; aspergillus ochraceus; strain ... See more keywords