Methoxylated 2'-hydroxychalcones as antiparasitic hit compounds.
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DOI: 10.1016/j.ejmech.2016.12.017
Abstract: Chalcones display a broad spectrum of pharmacological activities. Herein, a series of 2'-hydroxy methoxylated chalcones was synthesized and evaluated towards Trypanosoma brucei, Trypanosoma cruzi and Leishmania infantum. Among the synthesized library, compounds 1, 3, 4,… read more here.
Keywords: hit compounds; methoxylated hydroxychalcones; chemistry; hydroxychalcones antiparasitic ... See more keywords