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Published in 2020 at "Journal of Clinical Pharmacology"
DOI: 10.1002/jcph.1646
Abstract: The world is facing a frightening pandemic due to coronavirus disease 2019 (COVID-19) caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV2) with thousands of severe infections and fatalities. Since no therapy has proven… read more here.
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Published in 2020 at "Internal and Emergency Medicine"
DOI: 10.1007/s11739-020-02388-y
Abstract: Since the emerging of the new coronavirus disease (COVID19) with its staggering worldwide morbidity and mortality, the scientific community has been placed under extraordinary pressure to find safe and effective treatments, pending the availability of… read more here.
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Published in 2020 at "International Journal of Antimicrobial Agents"
DOI: 10.1016/j.ijantimicag.2020.105949
Abstract: Abstract Background Chloroquine and hydroxychloroquine have been found to be efficient on SARS-CoV-2, and reported to be efficient in Chinese COV-19 patients. We evaluate the role of hydroxychloroquine on respiratory viral loads. Patients and methods… read more here.
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Published in 2020 at "International Journal of Cardiology"
DOI: 10.1016/j.ijcard.2020.05.036
Abstract: Abstract Background Hydroxychloroquine and azithromycin combination therapy is often prescribed for coronavirus disease 2019 (COVID-19). Electrocardiographic (ECG) monitoring is warranted because both medications cause corrected QT-interval (QTc) prolongation. Whether QTc duration significantly varies during the… read more here.
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Published in 2020 at "Travel Medicine and Infectious Disease"
DOI: 10.1016/j.tmaid.2020.101663
Abstract: Abstract Background We need an effective treatment to cure COVID-19 patients and to decrease virus carriage duration. Methods We conducted an uncontrolled non-comparative observational study in a cohort of 80 relatively mildly infected inpatients treated… read more here.
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Published in 2020 at "Journal of Molecular and Cellular Cardiology"
DOI: 10.1016/j.yjmcc.2020.12.014
Abstract: The coronavirus disease 2019 (COVID-19) outbreak caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has become a global pandemic as declared by World Health Organization (WHO). In the absence of an effective treatment in… read more here.
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Published in 2020 at "Journal of Cardiovascular Electrophysiology"
DOI: 10.1111/jce.14594
Abstract: Abstract Combined use of hydroxychloroquine and azithromycin was globally adopted, in part due to paucity and high cost of alternative therapies. However the utility of these medications has been questioned; and thus safety becomes a… read more here.
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Published in 2020 at "Journal of Cardiovascular Electrophysiology"
DOI: 10.1111/jce.14721
Abstract: We thank Medina et al. for their interest in our recent work on QTc prolongation associated with treatment of COVID‐19 patients with hydroxychloroquine and azithromycin. As they appropriately point out in their letter, genetic variation… read more here.
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Published in 2021 at "Cardiovascular Therapeutics"
DOI: 10.1155/2021/6683098
Abstract: Background Hydroxychloroquine with or without azithromycin was one of the common therapies at the beginning of the COVID-19 pandemic. They can prolong QT interval, cause torsade de pointes, and lead to sudden cardiac death. We… read more here.
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Published in 2021 at "Current drug safety"
DOI: 10.2174/1574886316666210727152609
Abstract: BACKGROUND The treatment of COVID-19 disease remains a dilemma so far because there is no approved therapy for it. This study aimed to evaluate the use of hydroxychloroquine and azithromycin combination in treatment. OBJECTIVE This… read more here.
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Published in 2020 at "Journal of the College of Physicians and Surgeons--Pakistan : JCPSP"
DOI: 10.29271/jcpsp.2020.supp2.s153
Abstract: OBJECTIVE To assess and identify the risk of prolonged QT about hydroxychloroquine (HQ) and azithromycin (AZ) used in the treatment of patients with COVID-19. STUDY DESIGN Cohort study. PLACE AND DURATION OF STUDY Kartal Dr.… read more here.