12‐Hydroxyeicosatetraenoic acid levels are increased in actinic keratoses and squamous cell carcinoma
Sign Up to like & getrecommendations! Published in 2018 at "Journal of the American Academy of Dermatology"
DOI: 10.1016/j.jaad.2018.05.1251
Abstract: Author(s): Laquer, Vivian; Dellinger, Ryan W; Mannering, Irene; Garcia, Angela Gomez; Abraham, Vivek; Pavlis, Janelle; Liu-Smith, Feng; De Feraudy, Sebastien; Meyskens, Frank L; Kelly, Kristen M read more here.
Keywords: increased actinic; levels increased; acid levels; actinic keratoses ... See more keywords
Key role of 15-LO/15-HETE in angiogenesis and functional recovery in later stages of post-stroke mice
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/srep46698
Abstract: This study sought to clarify the effects of 15-lipoxygenase/15-hydroxyeicosatetraenoic acid in angiogenesis and neurological functional recovery after cerebral ischaemic stroke in mice. In vivo, we performed behavioural tests to determine functional recovery after stroke. Double… read more here.
Keywords: recovery; angiogenesis; hydroxyeicosatetraenoic acid; functional recovery ... See more keywords
12(S)‐hydroxyeicosatetraenoic acid impairs vascular endothelial permeability by altering adherens junction phosphorylation levels and affecting the binding and dissociation of its components in high glucose‐induced vascular injury
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Diabetes Investigation"
DOI: 10.1111/jdi.12941
Abstract: Diabetes is an important risk factor for atherosclerotic disease. The initiating factor of atherosclerosis is local endothelial cell injury. The arachidonic acid metabolite, 12(S)‐hydroxyeicosatetraenoic acid (12[S]‐HETE), might be involved in this process. In recent years,… read more here.
Keywords: high glucose; hydroxyeicosatetraenoic acid; injury; vascular endothelial ... See more keywords
Inhibition of 20-hydroxyeicosatetraenoic acid biosynthesis by vitamin E analogs in human and bovine cytochrome P450 microsomes.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of animal physiology and animal nutrition"
DOI: 10.1111/jpn.13547
Abstract: Dairy cattle are predisposed to disease around the time of calving due to dysfunctional inflammatory responses. Oxylipids are lipid-derived mediators that regulate all aspects of the inflammatory response, and shifts in oxylipid profiles are correlated… read more here.
Keywords: cyp4f2; production; hete production; vitamin analogs ... See more keywords
5-hydroxyeicosatetraenoic acid controls androgen reduction in diverse types of human epithelial cells.
Sign Up to like & getrecommendations! Published in 2022 at "Endocrinology"
DOI: 10.1210/endocr/bqac191
Abstract: Androgens regulate broad physiologic and pathologic processes, including external genitalia development, prostate cancer progression, and anti-inflammatory effects in both cancer and asthma. In prostate cancer, several lines of evidence have implicated dietary and endogenous fatty… read more here.
Keywords: hydroxyeicosatetraenoic acid; acid controls; acid; fatty acids ... See more keywords