Articles with "hydroxyestra diene" as a keyword



10β-Hydroxyestra-1,4-diene-3,17-dione as potential antiproliferative agent: in vitro biological evaluation and in silico studies

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Published in 2022 at "Natural Product Research"

DOI: 10.1080/14786419.2022.2039136

Abstract: Abstract 10β-Hydroxyestra-1,4-diene-3,17-dione (HEDD) is a natural product described as having neuroprotective activity. However, the cytotoxic properties of this quinol are barely studied. Thus, the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assay was performed in six cell lines (MCF-7, T47-D,… read more here.

Keywords: antiproliferative agent; hydroxyestra diene; diene dione; potential antiproliferative ... See more keywords