The Landscape and Potential Regulatory Mechanism of Lysine 2-Hydroxyisobutyrylation of Protein in End-Stage Renal Disease.
Sign Up to like & getrecommendations! Published in 2021 at "Nephron"
DOI: 10.1159/000518424
Abstract: BACKGROUND Acetylation has a vital role in the pathogenesis of end-stage renal disease (ESRD). Lysine 2-hydroxyisobutyrylation (Khib) is a novel type of acetylation. In this study, we aimed to reveal the key features of Khib… read more here.
Keywords: renal disease; hydroxyisobutyrylation; stage renal; end stage ... See more keywords
Global landscape of 2-hydroxyisobutyrylation in human pancreatic cancer
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2022.1001807
Abstract: As a new type of post-translational modification (PTM), lysine 2-hydroxyisobutyrylation (Khib) was firstly identified in histones and functioned as a regulator of transactivation in mammals. However, the role of Khib proteins remains to be investigated.… read more here.
Keywords: landscape hydroxyisobutyrylation; pancreatic cancer; modified proteins; hydroxyisobutyrylation ... See more keywords