HIF prolyl hydroxylase 2/3 deletion disrupts astrocytic integrity and exacerbates neuroinflammation.
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DOI: 10.1002/glia.24380
Abstract: Astrocytes constitute the parenchymal border of the blood-brain barrier (BBB), modulate the exchange of soluble and cellular elements, and are essential for neuronal metabolic support. Thus, astrocytes critically influence neuronal network integrity. In hypoxia, astrocytes… read more here.
Keywords: integrity; prolyl hydroxylase; hydroxylase deletion; hif prolyl ... See more keywords