HIF-α Prolyl Hydroxylase Inhibitors and Their Implications for Biomedicine: A Comprehensive Review
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DOI: 10.3390/biomedicines9050468
Abstract: Oxygen is essential for the maintenance of the body. Living organisms have evolved systems to secure an oxygen environment to be proper. Hypoxia-inducible factor (HIF) plays an essential role in this process; it is a… read more here.
Keywords: hif prolyl; hif; inhibitors implications; hydroxylase inhibitors ... See more keywords
Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibitors and Iron Metabolism
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24033037
Abstract: The production of erythropoietin (EPO), the main regulator of erythroid differentiation, is regulated by hypoxia-inducible factor (HIF). HIF2α seems to be the principal regulator of EPO transcription, but HIF1α and 3α also may have additional… read more here.
Keywords: prolyl hydroxylase; inducible factor; iron; hypoxia inducible ... See more keywords