Polychlorinated biphenyls and their hydroxylated metabolites in the serum of e-waste dismantling workers from eastern China
Sign Up to like & getrecommendations! Published in 2017 at "Environmental Geochemistry and Health"
DOI: 10.1007/s10653-017-9958-x
Abstract: A number of studies have reported on the exposure of e-waste dismantling workers to significantly high concentrations of halogenated organic pollutants such as polychlorinated biphenyls (PCBs) and polybrominated diphenyl ethers. Such exposure can have adverse… read more here.
Keywords: hydroxylated metabolites; waste dismantling; polychlorinated biphenyls; waste ... See more keywords
Assessment of Polychlorinated Biphenyls and Their Hydroxylated Metabolites in Postmortem Human Brain Samples: Age and Brain Region Differences
Sign Up to like & getrecommendations! Published in 2022 at "Environmental Science & Technology"
DOI: 10.1021/acs.est.2c00581
Abstract: Exposure to polychlorinated biphenyls (PCBs) and their hydroxylated metabolites (OH-PCBs) has been implicated in neurodevelopmental disorders. However, the distribution of PCBs and OH-PCBs in the human brain has not been characterized. This study investigated the… read more here.
Keywords: polychlorinated biphenyls; brain; human brain; brain samples ... See more keywords
Human CYP2A6, CYP2B6, AND CYP2E1 Atropselectively Metabolize Polychlorinated Biphenyls to Hydroxylated Metabolites.
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DOI: 10.1021/acs.est.8b05250
Abstract: Exposure to chiral polychlorinated biphenyls (PCBs) has been associated with neurodevelopmental disorders. Their hydroxylated metabolites (OH-PCBs) are also potentially toxic to the developing human brain; however, the formation of OH-PCBs by human cytochrome P450 (P450)… read more here.
Keywords: hydroxylated metabolites; cyp2a6 cyp2b6; polychlorinated biphenyls; cyp2e1 ... See more keywords