Quantification of Global DNA Hydroxymethylation Level Using UHRF2 SRA-Luciferase Based on Bioluminescence Resonance Energy Transfer.
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DOI: 10.1021/acs.analchem.1c05619
Abstract: 5-Methylcytosine (5mC) plays an important role in the regulation of gene expression. Ten-eleven translocation (TET) continuously oxidizes 5mC to 5-hydroxymethylcytosine (5hmC), 5-formylcytosine (5fC), and 5-carboxylcytosine (5caC). High levels of 5hmC are found in the brain… read more here.
Keywords: hydroxymethylation level; dna; hydroxymethylation; uhrf2 sra ... See more keywords