Dysregulation and prognostic potential of 5-methylcytosine (5mC), 5-hydroxymethylcytosine (5hmC), 5-formylcytosine (5fC), and 5-carboxylcytosine (5caC) levels in prostate cancer
Sign Up to like & getrecommendations! Published in 2018 at "Clinical Epigenetics"
DOI: 10.1186/s13148-018-0540-x
Abstract: BackgroundPrognostic tools for prostate cancer (PC) are inadequate and new molecular biomarkers may improve risk stratification. The epigenetic mark 5-hydroxymethylcytosine (5hmC) has recently been proposed as a novel candidate prognostic biomarker in several malignancies including… read more here.
Keywords: formylcytosine 5fc; hydroxymethylcytosine 5hmc; 5cac levels; prostate cancer ... See more keywords
Genome-wide 5-hydroxymethylcytosine (5hmC) reassigned in Pten-depleted mESCs along neural differentiation
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2022.956604
Abstract: DNA methylation and hydroxymethylation have been implicated in the regulatory dynamics of gene expression in normal development and differentiation. 5-Hydroxymethylcytosine (5hmC), created by the ten-eleven translocation (TET) protein-catalyzed oxidation of 5-methylcytosine (5mC), is abundant in… read more here.
Keywords: differentiation; genome wide; midbrain hindbrain; hydroxymethylcytosine 5hmc ... See more keywords