Articles with "hydroxypropyl cyclodextrin" as a keyword



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Use of hydroxypropyl β-cyclodextrin hybrid monolithic material as adsorbent for dispersive solid-phase extraction of fluoroquinolones from environmental water samples.

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Published in 2022 at "Journal of separation science"

DOI: 10.1002/jssc.202200054

Abstract: In this study, the hydroxypropyl β-cyclodextrin hybrid monolithic material was fabricated and firstly applied as adsorbent for dispersive solid-phase extraction coupled with high-performance liquid chromatography to detect trace-level seven fluoroquinolones in water samples. The prepared… read more here.

Keywords: hydroxypropyl cyclodextrin; material; cyclodextrin hybrid; monolithic material ... See more keywords
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Chiral analysis of -alanyl-d,l-tyrosine and its derivatives and estimation of binding constants of their complexes with 2-hydroxypropyl-β-cyclodextrin by capillary electrophoresisS.

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Published in 2022 at "Journal of separation science"

DOI: 10.1002/jssc.202200158

Abstract: Chiral CE methods were developed for elucidation of l- or d-configuration of tyrosine residue in antimicrobial dipeptide β-alanyl-tyrosine (β-Ala-Tyr) isolated from hemolymph of larvae of fleshfly Neobellieria bullata and for evaluation of enantiopurity of its… read more here.

Keywords: alanyl tyrosine; ala tyr; hydroxypropyl cyclodextrin;
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Minoxidil–2-hydroxypropyl-β-cyclodextrin inclusion complexes: characterization and in vivo evaluation of an aqueous solution for hair growth in rats

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Published in 2017 at "Journal of Inclusion Phenomena and Macrocyclic Chemistry"

DOI: 10.1007/s10847-017-0705-9

Abstract: Minoxidil dissolved in organic solvents is commonly used in the treatment of androgenic alopecia because it is hydrophobic and poorly soluble in water. The aim of this investigation was to develop an aqueous minoxidil solution… read more here.

Keywords: inclusion; minoxidil; hydroxypropyl cyclodextrin; inclusion complexes ... See more keywords
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Preparation and evaluation of binary and ternary inclusion complexes of fenofibrate/hydroxypropyl-β-cyclodextrin

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Published in 2018 at "Journal of Inclusion Phenomena and Macrocyclic Chemistry"

DOI: 10.1007/s10847-018-0793-1

Abstract: This study aimed to investigate the effect of hydroxypropyl methylcellulose on the complexation of fenofibrate and hydroxypropyl-β-cyclodextrin (HP-β-CD). Initially, phase solubility studies with an excess amount of drug in the HP-β-CD solutions with and without… read more here.

Keywords: inclusion; complexes fenofibrate; binary ternary; hydroxypropyl cyclodextrin ... See more keywords
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Phase solubility and thermoanalytical studies of the inclusion complex formation between curcumin and hydroxypropyl-β-cyclodextrin in hydroalcoholic solutions

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Published in 2020 at "Journal of Thermal Analysis and Calorimetry"

DOI: 10.1007/s10973-020-10381-y

Abstract: Curcumin (CURC) is endowed with many pharmacological properties, among these anti-inflammatory, antioxidant, antimicrobial, and anticancer activity. Unfortunately, CURC is basically water-insoluble and undergoes a rapid photodegradation, chemical degradation, and metabolism. CURC stability and solubility can… read more here.

Keywords: complex formation; formation; hydroxypropyl cyclodextrin; inclusion complex ... See more keywords
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2-Hydroxypropyl-β-cyclodextrin Ototoxicity in Adult Rats: Rapid Onset and Massive Destruction of Both Inner and Outer Hair Cells Above a Critical Dose

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Published in 2020 at "Neurotoxicity Research"

DOI: 10.1007/s12640-020-00252-7

Abstract: 2-Hydroxypropyl-β-cyclodextrin (HPβCD), a cholesterol chelator, is being used to treat diseases associated with abnormal cholesterol metabolism such as Niemann-Pick C1 (NPC1). However, the high doses of HPβCD needed to slow disease progression may cause hearing… read more here.

Keywords: ototoxicity; hydroxypropyl cyclodextrin; outer hair; loss ... See more keywords
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Comparative effects of trehalose and 2-hydroxypropyl-β-cyclodextrin on aggregation of UV-irradiated muscle glycogen phosphorylase b.

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Published in 2019 at "Biochimie"

DOI: 10.1016/j.biochi.2019.08.006

Abstract: Chemical chaperones are a class of small molecules which enhance folding and prevent aggregation of proteins. Investigation of their effects on the processes of protein aggregation is of importance for further understanding of implication of… read more here.

Keywords: aggregation; trehalose hydroxypropyl; hydroxypropyl cyclodextrin; aggregation irradiated ... See more keywords
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New potential application of hydroxypropyl-β-cyclodextrin in solid self-nanoemulsifying drug delivery system and solid dispersion.

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Published in 2021 at "Carbohydrate polymers"

DOI: 10.1016/j.carbpol.2021.118433

Abstract: The purpose of this study was to use hydroxypropyl-β-cyclodextrin (HP-β-CD) as a novel carrier in solid SNEDDS and solid dispersions to enhance the solubility and oral bioavailability of poorly water-soluble dexibuprofen. The novel dexibuprofen-loaded solid… read more here.

Keywords: dexibuprofen; solid snedds; solid dispersion; drug ... See more keywords
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Use of hydroxypropyl β-cyclodextrin as a dual functional component in xanthan hydrogel for sustained drug release and antibacterial activity

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Published in 2020 at "Colloids and Surfaces A: Physicochemical and Engineering Aspects"

DOI: 10.1016/j.colsurfa.2019.124368

Abstract: Abstract A hydrogel of xanthan gum (XG) was improved by crosslinking hydroxypropyl β-cyclodextrin (HPCD) physically to construct a novel drug delivery system. This hydrogel was full of the textures due to directional self-aggregations of XG… read more here.

Keywords: hydrogel; microscopy; drug; hydroxypropyl cyclodextrin ... See more keywords
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Antioxidant and antimicrobial polyvinyl alcohol electrospun nanofibers containing baicalein-hydroxypropyl-β-cyclodextrin inclusion complex

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Published in 2021 at "Colloids and Surfaces A: Physicochemical and Engineering Aspects"

DOI: 10.1016/j.colsurfa.2021.126135

Abstract: Abstract A novel antioxidant and antibacterial material were prepared by incorporating Baicalein-Hydroxypropyl-β-Cyclodextrin inclusion complex (Ba-IC) into polyvinyl alcohol (PVA) nanofibers (PVA-Ba-IC-NF) via electrospinning method. Herein, PVA was used as the polymeric matrix for the nanofibers.… read more here.

Keywords: hydroxypropyl cyclodextrin; polyvinyl alcohol; cyclodextrin inclusion; baicalein ... See more keywords
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Hydroxypropyl-ß-cyclodextrin as a membrane protectant during freeze-drying of hydrogenated and non-hydrogenated liposomes and molecule-in-cyclodextrin-in- liposomes: Application to trans-anethole.

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Published in 2018 at "Food chemistry"

DOI: 10.1016/j.foodchem.2017.10.144

Abstract: The effect of hydrogenation of phospholipids on the characteristics of freeze-dried liposomes was investigated using hydroxypropyl-ß-cyclodextrin (HP-ß-CD) as membrane protectant. The ethanol-injection method was applied to prepare liposomes using hydrogenated (Phospholopion-90H and 80H) and non-hydrogenated… read more here.

Keywords: freeze drying; cyclodextrin; membrane protectant; hydroxypropyl cyclodextrin ... See more keywords