3,2-Hydroxypyridinone-Grafted Chitosan Oligosaccharide Nanoparticles as Efficient Decorporation Agents for Simultaneous Removal of Uranium and Radiation-Induced Reactive Oxygen Species in Vivo.
Sign Up to like & getrecommendations! Published in 2018 at "Bioconjugate chemistry"
DOI: 10.1021/acs.bioconjchem.8b00711
Abstract: Most of the key radionuclides in the nuclear fuel cycle, such as actinides, possess a combination of heavy metal chemotoxicity and radiotoxicity and therefore represent a severe threat to the ecological environment and public safety.… read more here.
Keywords: uranium; radiation induced; chitosan oligosaccharide; decorporation ... See more keywords
Hydroxypyridinone and 5-Aminolaevulinic Acid Conjugates for Photodynamic Therapy.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of medicinal chemistry"
DOI: 10.1021/acs.jmedchem.7b00346
Abstract: Photodynamic therapy (PDT) is a promising treatment strategy for malignant and nonmalignant lesions. 5-Aminolaevulinic acid (ALA) is used as a precursor of the photosensitizer, protoporphyrin IX (PpIX), in dermatology and urology. However, the effectiveness of… read more here.
Keywords: hydroxypyridinone; ppix; photodynamic therapy; aminolaevulinic acid ... See more keywords
In situ beam reduction of Pu(IV) and Bk(IV) as a route to trivalent transuranic coordination complexes with hydroxypyridinone chelators
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Synchrotron Radiation"
DOI: 10.1107/s1600577522000200
Abstract: X-ray absorption spectroscopy was used to probe the interactions between an octadentate hydroxypyridinone chelator and two transuranic elements in microgram quantities – plutonium and berkelium – within buffered solutions. Despite the precedence for chelation-driven stabilization… read more here.
Keywords: coordination complexes; reduction route; beam reduction; situ beam ... See more keywords