Hydroxypyridinone-Based Iron Chelators with Broad-Ranging Biological Activities.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of medicinal chemistry"
DOI: 10.1021/acs.jmedchem.0c01480
Abstract: Iron plays an essential role in all living cells because of its unique chemical properties. It is also the most abundant trace element in mammals. However, when iron is present in excess or inappropriately located,… read more here.
Keywords: iron chelators; chelators broad; based iron; broad ranging ... See more keywords
A 3,2-Hydroxypyridinone-based Decorporation Agent that Removes Uranium from Bones In Vivo
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DOI: 10.1038/s41467-019-10276-z
Abstract: Searching for actinide decorporation agents with advantages of high decorporation efficiency, minimal biological toxicity, and high oral efficiency is crucial for nuclear safety and the sustainable development of nuclear energy. Removing actinides deposited in bones… read more here.
Keywords: removes uranium; decorporation; hydroxypyridinone based; ligand ... See more keywords