Metal‐chelating 3‐hydroxypyrimidine‐2,4‐diones inhibit human cytomegalovirus pUL89 endonuclease activity and virus replication
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DOI: 10.1016/j.antiviral.2018.01.015
Abstract: ABSTRACT Human cytomegalovirus terminase complex cleaves the concatemeric genomic viral DNA into unit lengths during genome packaging and particle assembly. Terminase complex ATPase and endonuclease activity is provided by the viral protein pUL89. pUL89 is… read more here.
Keywords: endonuclease activity; replication; pul89; hydroxypyrimidine diones ... See more keywords