Addition of hydroxyurea (hydroxycarbamide) enhances the efficacy of fludarabine/cytarabine-based salvage regimens against acute myeloid leukaemia.
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DOI: 10.1111/bjh.70180
Abstract: Despite intensive treatment, patients with relapsed or refractory acute myeloid leukaemia (AML) have a dismal prognosis. A cornerstone therapy for relapsed/refractory AML is a combination of fludarabine (F‐ara‐A) and cytarabine (ara‐C), so‐called FLA. As the… read more here.
Keywords: myeloid leukaemia; hydroxyurea hydroxycarbamide; acute myeloid; cytarabine ... See more keywords