Regulation of 25‐hydroxyvitamin D‐1‐hydroxylase and 24‐hydroxylase in keratinocytes by PTH and FGF23
Sign Up to like & getrecommendations! Published in 2018 at "Experimental Dermatology"
DOI: 10.1111/exd.13760
Abstract: Renal 25‐hydroxyvitamin D‐1α‐hydroxylase (1αOHase, CYP27B1) and 24‐hydroxylase (24OHase, CYP24A1) are tightly regulated. However, little is known about the regulation of 1α(OH)ase and 24(OH)ase in extrarenal tissue such as the epidermis. This study was to determine… read more here.
Keywords: hydroxylase; ase; differentiation; hacat ... See more keywords
25-hydroxyvitamin D-1α-hydroxylase (CYP27B1) induces ectopic calcification
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Clinical Biochemistry and Nutrition"
DOI: 10.3164/jcbn.22-16
Abstract: Vascular calcification is an important pathogenesis related to cardiovascular disease and high mortality rate in chronic kidney disease (CKD) patients. It has been well-known that hyperphosphatemia induces osteochondrogenic transition of vascular smooth muscle cells (VSMCs)… read more here.
Keywords: calcification; hydroxyvitamin hydroxylase; cyp27b1; high phosphate ... See more keywords
Calcitriol-Mediated Hypercalcemia, Somatostatin Receptors Expression and 25-Hydroxyvitamin D3-1α- Hydroxylase in GIST Tumors
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2021.812385
Abstract: Hypercalcemia is a common complication in cancer patients Mainly caused by Parathyroid hormone-related protein (PTHrP) secretion and metastasis. Calcitriol secretion is a rare source of hypercalcemia in solid tumors, especially in gastrointestinal stromal tumors (GIST).… read more here.
Keywords: calcitriol mediated; gist; hypercalcemia; hydroxyvitamin hydroxylase ... See more keywords