Hygiene Hypothesis in Asthma Development: Is Hygiene to Blame?
Sign Up to like & getrecommendations! Published in 2017 at "Archives of medical research"
DOI: 10.1016/j.arcmed.2017.11.009
Abstract: Industrialized countries have registered epidemic rates on allergic diseases, such as hay fever, asthma, eczema, and food allergies. The Hygiene Hypothesis was born from work made by Dr. David Strachan, who observed that younger siblings… read more here.
Keywords: hypothesis asthma; hypothesis; asthma development; asthma ... See more keywords
Multiple sclerosis, the microbiome, TLR2, and the hygiene hypothesis.
Sign Up to like & getrecommendations! Published in 2019 at "Autoimmunity reviews"
DOI: 10.1016/j.autrev.2019.102430
Abstract: The pathophysiology of autoimmune diseases such as Multiple Sclerosis (MS) involves a complex interaction between genetic and environmental factors. Studies of monozygotic twins suggest a significant role for environmental factors in susceptibility to MS. Numerous… read more here.
Keywords: microbiome; multiple sclerosis; role; hypothesis ... See more keywords
Does the Hygiene Hypothesis Explain COVID-19 Cases and Death? A Global Analysis
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Infectious Diseases"
DOI: 10.1016/j.ijid.2021.12.129
Abstract: Purpose At the start of the COVID-19 pandemic there was widespread speculation on the role of the hygiene hypothesis in the incidence and mortality of COVID-19. This study sought to determine if such a correlation… read more here.
Keywords: analysis; hygiene hypothesis; hypothesis; covid ... See more keywords
Evolution of the hygiene hypothesis into biota alteration theory: what are the paradigms and where are the clinical applications?
Sign Up to like & getrecommendations! Published in 2018 at "Microbes and infection"
DOI: 10.1016/j.micinf.2017.11.001
Abstract: For thousands of years, changes in human cultures have altered the biota associated with the human body, and those alterations have strongly influenced human health. The hygiene hypothesis has evolved over the past 30 years… read more here.
Keywords: hygiene hypothesis; alteration theory; biota alteration;
Hygiene hypothesis: association between hygiene and asthma among preschool children in Lebanon.
Sign Up to like & getrecommendations! Published in 2021 at "Allergologia et immunopathologia"
DOI: 10.15586/aei.v49i1.41
Abstract: OBJECTIVES To validate a scale to assess the hygiene hypothesis and the association between hygiene and asthma among Lebanese preschool children aged 3-5 years. METHODS This cross-sectional study, conducted between November 2018 and March 2019,… read more here.
Keywords: hygiene; association; asthma; hygiene hypothesis ... See more keywords
Revisiting the Hygiene Hypothesis in the Context of Autoimmunity
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2020.615192
Abstract: Initially described for allergic diseases, the hygiene hypothesis was extended to autoimmune diseases in the early 2000s. A historical overview allows appreciation of the development of this concept over the last two decades and its… read more here.
Keywords: hypothesis context; role; revisiting hygiene; hypothesis ... See more keywords
Hygiene Hypothesis Indicators and Prevalence of Antinuclear Antibodies in US Adolescents
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.789379
Abstract: Autoimmunity prevalence, as measured by antinuclear antibodies (ANA), is increasing in U.S. adolescents. Improved hygiene and cleaner environments in childhood may reduce exposure to infections and other immune challenges, resulting in improper immune responses to… read more here.
Keywords: hypothesis indicators; prevalence antinuclear; hygiene hypothesis; indicators prevalence ... See more keywords
The Interactive Roles of Lipopolysaccharides and dsRNA/Viruses on Respiratory Epithelial Cells and Dendritic Cells in Allergic Respiratory Disorders: The Hygiene Hypothesis
Sign Up to like & getrecommendations! Published in 2017 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms18102219
Abstract: The original hygiene hypothesis declares “more infections in early childhood protect against later atopy”. According to the hygiene hypothesis, the increased incidence of allergic disorders in developed countries is explained by the decrease of infections.… read more here.
Keywords: epithelial cells; th2 skewing; cells dendritic; dendritic cells ... See more keywords