Preliminary evaluation of a small interfering RNA molecular probe targeting murine double minute 2 in breast cancer
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DOI: 10.1097/mnm.0000000000001582
Abstract: Introduction Murine double minute 2 (MDM2) is an oncogene that is important in tumorigenesis, tumor metastasis and chemotherapy resistance. We aimed to synthesize a molecular imaging probe, 99mTc-HYNIC-siRNA 1489, which could specifically bind to MDM2.… read more here.
Keywords: hynic sirna; sirna; 99mtc hynic; sirna 1489 ... See more keywords