Hydroxyproline Metabolism and Oxalate Synthesis in Primary Hyperoxaluria.
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DOI: 10.1681/asn.2017040390
Abstract: Background Endogenous oxalate synthesis contributes to calcium oxalate stone disease and is markedly increased in the inherited primary hyperoxaluria (PH) disorders. The incomplete knowledge regarding oxalate synthesis complicates discovery of new treatments. Hydroxyproline (Hyp) metabolism… read more here.
Keywords: primary hyperoxaluria; oxalate synthesis; metabolism; hyp metabolism ... See more keywords