Split2 Protein-Ligation Generates Active IL-6-Type Hyper-Cytokines from Inactive Precursors.
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DOI: 10.1021/acssynbio.7b00208
Abstract: Trans-signaling of the major pro- and anti-inflammatory cytokines Interleukin (IL)-6 and IL-11 has the unique feature to virtually activate all cells of the body and is critically involved in chronic inflammation and regeneration. Hyper-IL-6 and… read more here.
Keywords: split2 protein; cytokine; hyper; trans signaling ... See more keywords