EPC1/TIP60-Mediated Histone Acetylation Facilitates Spermiogenesis in Mice
Sign Up to like & getrecommendations! Published in 2017 at "Molecular and Cellular Biology"
DOI: 10.1128/mcb.00082-17
Abstract: ABSTRACT Global histone hyperacetylation is suggested to play a critical role for replacement of histones by transition proteins and protamines to compact the genome during spermiogenesis. However, the underlying mechanisms for hyperacetylation-mediated histone replacement remains… read more here.
Keywords: histone acetylation; mediated histone; hyperacetylation; tip60 mediated ... See more keywords
Global Lysine Acetylome Analysis of LPS-Stimulated HepG2 Cells Identified Hyperacetylation of PKM2 as a Metabolic Regulator in Sepsis
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DOI: 10.3390/ijms22168529
Abstract: Sepsis-induced liver dysfunction (SILD) is a common event and is strongly associated with mortality. Establishing a causative link between protein post-translational modification and diseases is challenging. We studied the relationship among lysine acetylation (Kac), sirtuin… read more here.
Keywords: sepsis; stimulated hepg2; lps stimulated; hepg2 cells ... See more keywords