Molecular interplay between hyperactive mammalian target of rapamycin signaling and Alzheimer’s disease neuropathology in the NS-Pten knockout mouse model
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DOI: 10.1097/wnr.0000000000001081
Abstract: Dysregulation of the PI3K/Akt/mTOR signaling cascade has been associated with the pathology of neurodegenerative disorders, specifically Alzheimer’s disease (AD). Both in-vivo models and post-mortem brain samples of individuals with AD have commonly shown hyperactivation of… read more here.
Keywords: alzheimer disease; mammalian target; hyperactive mammalian; pathology ... See more keywords