Articles with "hyperactive myc" as a keyword



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Targeting the ubiquitin‐proteasome system in a pancreatic cancer subtype with hyperactive MYC

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Published in 2020 at "Molecular Oncology"

DOI: 10.1002/1878-0261.12835

Abstract: The myelocytomatosis oncogene (MYC) is an important driver in a subtype of pancreatic ductal adenocarcinoma (PDAC). However, MYC remains a challenging therapeutic target; therefore, identifying druggable synthetic lethal interactions in MYC‐active PDAC may lead to… read more here.

Keywords: pdac; hyperactive myc; proteasome system; myc ... See more keywords