Cuprizone-induced dopaminergic hyperactivity and locomotor deficit in zebrafish larvae
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DOI: 10.2139/ssrn.3970449
Abstract: Cuprizone (CPZ) is a copper-chelator and toxic to mitochondria. Recent studies have shown oligodendrocyte (OL) loss and demyelination along with dopamine (DA) increase and behavioral abnormalities in CPZ-exposed mice, demonstrating its application in schizophrenia research.… read more here.
Keywords: cpz; hyperactivity locomotor; zebra fish; locomotor deficit ... See more keywords