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Published in 2019 at "FEBS Open Bio"
DOI: 10.1002/2211-5463.12723
Abstract: Polycystic ovary syndrome (PCOS) is a major cause of anovulatory sterility in women, and most PCOS patients exhibit hyperandrogenism (HA). Liver kinase b1 (LKB1) is a tumor suppressor that has recently been reported to be…
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Keywords:
via igf;
igf signaling;
androgen synthesis;
hyperandrogenism ... See more keywords
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Published in 2019 at "Molecular Reproduction and Development"
DOI: 10.1002/mrd.23239
Abstract: Maternal nutritional status programs the development of several systems in female offspring, with effects that depend on the severity, duration, and window of development when the nutritional perturbation is imposed. On the basis of the…
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Keywords:
pregnancy;
hyperandrogenism;
disease;
undernutrition ... See more keywords
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Published in 2018 at "Obesity"
DOI: 10.1002/oby.22198
Abstract: Obesity in females is often associated with metabolic complications and hyperandrogenism, but the sources of androgens are not completely understood. Therefore, this study investigated whether adipose tissue could be a source of androgens promoting hyperandrogenism…
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Keywords:
obese female;
tissue potential;
source;
hyperandrogenism ... See more keywords
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Published in 2017 at "EBioMedicine"
DOI: 10.1016/j.ebiom.2017.01.011
Abstract: Background Excessive androgen exposure during pregnancy has been suggested to induce diabetic phenotypes in offspring in animal models. The aim of this study was to investigate whether pregestational maternal hyperandrogenism in human influenced the glucose…
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Keywords:
showed increased;
hyperandrogenism;
igf2 expression;
born mothers ... See more keywords
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Published in 2021 at "Endocrinology and metabolism clinics of North America"
DOI: 10.1016/j.ecl.2020.12.002
Abstract: Evidence of clinical and/or biochemical androgen excess poses a unique differential in postmenopausal women. Some signs and symptoms of postmenopausal hyperandrogenism can be normal and attributed to the natural aging process. However, the causes of…
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Keywords:
androgen excess;
hyperandrogenism;
hyperandrogenism evaluation;
evaluation treatment ... See more keywords
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Published in 2018 at "Journal of Sports Sciences"
DOI: 10.1080/02640414.2018.1464620
Abstract: ABSTRACT The purpose of this study was to examine whether the difference in elite-standard track and field performance between women athletes with and without hyperandrogenism reaches the 10–12% difference in performance between men and women,…
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Keywords:
difference;
hyperandrogenism;
200m 800m;
elite standard ... See more keywords
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Published in 2018 at "Gynecological Endocrinology"
DOI: 10.1080/09513590.2017.1397114
Abstract: Abstract Hyperandrogenism is a condition affecting 5–10% of adolescents. The aim of this study was to evaluate the efficacy of very low dose of flutamide in the treatment of hyperandrogenism in adolescence. One hundred and…
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Keywords:
low dose;
hyperandrogenism;
treatment;
treatment hyperandrogenism ... See more keywords
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Published in 2020 at "Gynecological Endocrinology"
DOI: 10.1080/09513590.2020.1770724
Abstract: Abstract Objective Polycystic ovarian syndrome is a complex reproductive as well as endocrinological disorder characterized by anovulatory dysfunction, androgen excess and polycystic ovarian morphology. Hyperandrogenism is regarded as a cardinal feature of the disease. It…
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Keywords:
hyperandrogenism kashmiri;
polycystic ovarian;
hyperandrogenism;
cyp17 gene ... See more keywords
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Published in 2022 at "Obesity Facts"
DOI: 10.1159/000521571
Abstract: Introduction: Obesity in women is often associated with hyperandrogenism, but the role of adipose tissue (AT) in androgen synthesis remains unclear. Therefore, we studied whether AT could be a source of androgens promoting hyperandrogenism. Methods:…
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Keywords:
androgen production;
hyperandrogenism women;
adipose tissue;
depot specific ... See more keywords
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Published in 2022 at "Hormone Research in Paediatrics"
DOI: 10.1159/000526722
Abstract: Descriptions of probable PCOS can be found in ancient Roman writings and in Renaissance art. Attention to domesticated animal reproduction led ancient observers to understand the role of the testes in male phenotypes, proven experimentally…
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Keywords:
history polycystic;
premature;
endocrinology;
adrenarche ... See more keywords
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Published in 2019 at "Journal of the Endocrine Society"
DOI: 10.1210/js.2019-sat-291
Abstract: Abstract Background: Type A insulin resistance (IR) is a form of severe IR due to heterozygous mutations in the insulin receptor gene. It presents with acanthosis nigricans, IR, and hyperandrogenism in the absence of obesity…
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Keywords:
therapy;
treatment;
insulin;
hyperandrogenism ... See more keywords