Vitamin D receptor (VDR) contributes to the development of hypercalciuria by sensitizing VDR target genes to vitamin D in a genetic hypercalciuric stone-forming (GHS) rat model
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DOI: 10.1016/j.gendis.2020.09.001
Abstract: Abstract Human idiopathic hypercalciuria (IH) is the most common cause of calcium oxalate nephrolithiasis with perturbed calcium metabolism with increased bone resorption and decreased renal calcium reabsorption, which can be phenotype-copied in the genetic hypercalciuric… read more here.
Keywords: hypercalciuria; development; receptor; calcium ... See more keywords
Mutations in CLDN2 Are Not a Common Cause of Pediatric Idiopathic Hypercalciuria in Canada
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DOI: 10.1177/20543581221098782
Abstract: Background: Hypercalciuria is the most common risk factor for kidney stone formation, including in pediatric patients. However, the etiology is often unknown and children are frequently diagnosed with idiopathic hypercalciuria. Nearly 50% of children with… read more here.
Keywords: common cause; idiopathic hypercalciuria; hypercalciuria; kidney ... See more keywords
RF18 | PMON103 Hypercalciuria in Young Adults With Primary Hyperparathyroidism Is Less Likely to Resolve After a Successful Parathyroidectomy Compare to Older Adults
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DOI: 10.1210/jendso/bvac150.463
Abstract: Abstract Introduction Hypercalciuria is one of the reported complications in patients with primary hyperparathyroidism (PHPT). Profound hypercalciuria in the settings of renal stones is considered to be one of the indications for parathyroidectomy. However, limited… read more here.
Keywords: urine calcium; calcium; hypercalciuria; successful parathyroidectomy ... See more keywords
Association of hypercalciuria with vitamin D supplementation in patients undergoing ketogenic dietary therapy
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DOI: 10.3389/fnut.2022.970467
Abstract: Background Ketogenic dietary therapy (KDT) is used as an effective treatment for epilepsy. However, KDT carries the risk of bone health deterioration; therefore, vitamin D supplementation is required. Vitamin D replacement therapy in KDT has… read more here.
Keywords: hypercalciuria; therapy; vitamin supplementation; level ... See more keywords